Neuroscientist with over ten years of experience studying neurodegenerative diseases
Self-starter and independent researcher/consultant: initiated motor neuron disease research efforts in a pharmaceutical company, managed preclinical target development in multiple startups, and helped create a neurodegeneration challenge network in a foundation
Experienced manager with over five years of experience in leading, supervising and mentoring colleagues and students
Science writer with a passion for promoting STEM education for children and making science and wellness accessible to everyone
Ikiz B, Croll S, Stahl N, Murphy A, Macdonald L, Fralish M; Characterization of β-methylamino-L-alanine (BMAA) as a tool to study environmental-linked sporadic motor neuron disease; in preparation.
Ikiz B, Schaner M, Croll S, Bai Y, Fury W, Dominguez M, Zambrowicz B, Stahl N, Yancopoulos G, Murphy A, Macdonald L, LaCroix-Fralish M; Mice lacking Death Receptor 6 (Tnfrsf21) develop spontaneous, progressive motor neuron degeneration; Scientific Reports; in review.
Atanasio A, Decman V, White D, Ramos M, Ikiz B, Lee HC, Siao CJ, Brydges S, LaRosa E, Bai Y, Fury W, Burfeind P, Zamfirova R, Warshaw G, Orengo J, Oyejide A, Fralish M, Auerbach W, Poueymirou W, Freudenberg J, Gong G, Zambrowicz B, Valenzuela D, Yancopoulos G, Murphy A, Thurston G, Lai KM; C9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production, and glomerulonephropathy in mice; Scientific Reports. 2016 Mar 16; 6:23204.
Ikiz B, Alvarez MJ, Ré DB, Le Verche V, Politi K, Lotti F, Phani S, Pradhan R, Yu C, Croft GF, Jacquier A, Henderson CE, Califano A, Przedborski S; The Regulatory Machinery of Neurodegeneration in In Vitro Models of Amyotrophic Lateral Sclerosis; Cell Reports. 2015 Jul 14; 12(2):335-45.
Re DB, Le Verche V, Yu C, Amoroso MW, Politi KA, Phani S, Ikiz B, Hoffmann L, Koolen M, Nagata T, Papadimitriou D, Nagy P, Mitsumoto H, Kariya S, Wichterle H, Henderson CE, Przedborski S; Necroptosis drives motor neuron death in models of both sporadic and familial ALS; Neuron. 2014 Mar 5; 81(5):1001-8.
Le Verche V, Ikiz B, Jacquier A, Przedborski S, Re DB; Glutamate pathway implication in amyotrophic lateral sclerosis: what is the signal in the noise?; Journal of Receptor, Ligand and Channel Research. 2010 Dec; 4:1-22.
Papadimitriou D, Le Verche V, Jacquier A, Ikiz B, Przedborski S, Re DB; Inflammation in ALS and SMA: Sorting out the good from the evil; Neurobiology of Disease. 2010 Mar; 37(3):493-502.
Ikiz B, Przedborski S; A sequel to the tale of p25/Cdk5 in neurodegeneration; Neuron. 2008 Dec 10; 60(5):731-2.
Ikiz B, LaCroix-Fralish M, Croll SD; “Non-human animal exhibiting diminished upper and lower motor neuron function and sensory perception” US Patent Application 15/072,286; filed March 16, 2016 (non-provisional US application).
Atanasio A, Ikiz, B, Gong G, LaCroix-Fralish ML, Lai VK, Valenzuela DM; “Non-human animals having a disruption in a C9ORF72 locus” US Patent Application 15/165,307; filed May 26, 2016 (non-provisional US application).
Brunie Award for Stem Cell Research, Columbia University
Dean’s Academic Education Grant, Columbia University
Vice Provost Undergraduate Education Grant, Stanford University
Undergraduate Research Program Major Grant, Stanford University